3-Bromo-7-methoxyimidazo-[1,2-a]pyridine-8-carbonitrile - Names and Identifiers
3-Bromo-7-methoxyimidazo-[1,2-a]pyridine-8-carbonitrile - Physico-chemical Properties
Molecular Formula | C9H6BrN3O
|
Molar Mass | 252.07 |
Melting Point | >180oC (dec.) |
Solubility | Acetonitrile (Slightly), DMSO (Slightly) |
Appearance | Solid |
Color | Pale Orange to Light Orange |
Storage Condition | 2-8°C |
Sensitive | IRRITANT |
MDL | MFCD11504889 |
3-Bromo-7-methoxyimidazo-[1,2-a]pyridine-8-carbonitrile - Introduction
3-Bromo-7-methoxyimidazo-[1,2-a]pyridine-8-carbonitrile is an organic compound with the chemical formula C10H6BrN3O.
Its physical properties are as follows:
-Appearance: Colorless or light yellow solid
-Melting point: about 123-125 ℃
-Molecular weight: 253.08g/mol
-Solubility: Soluble in some organic solvents, such as chloroform, dimethyl sulfoxide and dichloromethane, insoluble in water
3-Bromo-7-methoxyimidazo-[1,2-a]pyridine-8-carbonitrile can be used for the following:
1. As a drug intermediate: It is an important intermediate for the synthesis of a series of drugs and biologically active compounds, such as antibacterial drugs, anti-tumor drugs, etc.
2. Pesticide field: In the agricultural field, this compound can be used to synthesize insect fungicides, weed herbicides, etc.
Regarding the method of synthesizing 3-Bromo-7-methoxyimidazo-[1,2-a]pyridine-8-carbonitrile, the common preparation routes are as follows:
1. First, 3-bromo-7-hydroxyimidazo [1,2-a] pyridine-8-one or substitutes are synthesized by reaction.
2. Then, by treating with a base under appropriate conditions, the hydroxyl group is replaced with a methoxy group.
3. Finally, replace the ketone group with a nitrile group by using an appropriate reagent or brominating agent.
The safety information for this compound has not been fully established, so appropriate safety measures need to be taken:
-Wear appropriate protective equipment during use, including goggles, gloves and lab coats.
-If you are exposed to the compound by accident, you should immediately flush the affected area with plenty of water and seek medical help.
-Pay attention to its explosion-proof performance during handling and storage, and keep it away from fire and heat sources.
Please note that when using this compound, you should refer to a reliable chemical substance safety data sheet (MSDS) and laboratory operation manual, and follow the correct operating procedures.
Last Update:2024-04-09 21:54:55